首页工具

登录

搜索结果

Search Results for " i factor "

Targets Recommended: Others

55

抑制剂 & 化合物

11

天然产物

1

化合物库

92

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name
L4100	TGF-β/Smad靶点化合物库		184 compounds
	184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合，用于高通量、高内涵筛选；

化合物库

TGF-β/Smad靶点化合物库

Cat.No: L4100

Compounds: 184

Cat. No.	Product Name	Target	Signaling Pathways
TP1122L	IGF-I 30-41 acetate(82177-09-1 free base) Insulin-like Growth Factor I (30-41) acetate	Others	Others
	IGF-I 30-41 acetate(82177-09-1 free base) (Insulin-like Growth Factor I (30-41) acetate) 是胰岛素样生长因子 I (IGF-I) 的氨基酸 30 至 41 片段。
T4026	SU5408 VEGFR2 Kinase Inhibitor I	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	SU5408 (VEGFR2 Kinase Inhibitor I) 是一种可渗透细胞的VEGFR2激酶抑制剂，其IC50=70 nM。
T80059	Complement factor I	Endogenous Metabolite	Metabolism
	Complement factor I，一丝氨酸蛋白酶，可与辅助因子H (FH)、补体受体1 (CR1/CD35)、C4结合蛋白 (C4BP) 或膜辅助因子蛋白 (MCP/CD46) 结合，调控液相及/或细胞表面补体系统的活性。
T4191	Multi-kinase inhibitor 1 Multi-kinase inhibitor I	Others; Bcr-Abl; PDGFR; c-Kit	Angiogenesis; Cytoskeletal Signaling; Others; Tyrosine Kinase/Adaptors
	Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) 是多激酶抑制剂。它有用于导致与酪氨酸激酶活性异常或失控有关的疾病或失调的潜力，特别是与c-Kit，PDGF-R，Bcr-abl 活性相关的疾病。
TD0099	Malachite green oxalate	Apoptosis; Others; IκB/IKK; NF-κB	Apoptosis; NF-κB; Others
	Malachite green oxalate 是一种三苯基甲烷染料，可用于检测酶促反应中磷酸盐的释放。它也是一种选择性IKBKE 抑制剂，在体内外均表现出抗肿瘤活性。
T0708	Oxaprozin 奥沙普秦,Oxaprozinum,Wy21743	NF-κB; COX	Immunology/Inflammation; Neuroscience; NF-κB
	Oxaprozin (Oxaprozinum) 是 COX-1和 COX-2的抑制剂，还能抑制 NF-κB 的活化，对人类血小板 COX-1 和 IL-1 刺激的人类滑膜细胞 COX-2 的 IC50值分别为 2.2 和 36 μM。
TP1122	IGF-I (30-41) Insulin-like Growth Factor I (30-41),IGF-I 30-41
	IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I).
TP1124	IGF-I (24-41) Insulin-like Growth Factor I (24-41),IGF-I 24-41
	IGF-I (24-41) is a 24-41 amino acid fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective
TP1121	IGF-I (30-41) TFA(82177-09-1,FREE) Insulin-like Growth Factor I (30-41) (TFA)
	IGF-I (30-41) (TFA) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I).
TP1123	IGF-I (24-41) TFA (135861-49-3 free base) Insulin-like Growth Factor I (24-41) (TFA),IGF-I (24-41) TFA
	IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, anti-inflammatory and cytoprotective actions).IGF-I (24-41) (TFA) is amino acids 24 to 41 fragment of Insulin-like Growth
T25465	GS143 GS-143,GS 143	IκB/IKK; E1/E2/E3 Enzyme; NF-κB	NF-κB; Ubiquitination
	GS-143 是选择性的IκBα泛素化抑制剂，抑制 SCFβTrCP1介导的IκBα泛素化作用，IC50=5.2 μM。GS143 抑制NF-κB 的活化和靶基因的转录，并且不抑制蛋白酶体的特性，并具有抗哮喘作用。
T1944	LDN-214117	ALK; TGF-beta/Smad	Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
	LDN214117 是一种高效的 ALK2 选择性抑制剂(IC50:22nM)，也是一种 BMP6 抑制剂(IC50:100nM)，对ALK5抑制力弱100倍。
T1083L	Theophylline monohydrate Quibron,茶碱一水合物	HDAC; PDE; Adenosine Receptor	Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Metabolism; Neuroscience
	Theophylline monohydrate (Quibron) 似乎抑制磷酸二酯酶和前列腺素的产生，调节钙通量和细胞内钙分布，并拮抗腺苷。茶碱是黄嘌呤的天然生物碱衍生物，从植物山茶花和小粒咖啡中分离出来。在生理上，该药剂可放松支气管平滑肌，产生血管舒张（脑血管除外），刺激中枢神经系统，刺激心肌，利尿，增加胃酸分泌；它还可以抑制炎症并改善横膈膜的收缩性。
TP1021	Urocortin, human Urocortin (human),Human urocortin,Human urocortin 1,Human urocortin I	CRFR	GPCR/G Protein
	Urocortin, human (Human urocortin I) 是由 40 个氨基酸组成的神经多肽，是选择性 CRF2受体激动剂，作用于 hCRF1(Ki:0.4 nM)、rCRF2α(Ki:0.3 nM)、 mCRF2β(Ki:0.5 nM)。
T2160	Suramin Sodium Salt 苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060	Apoptosis; Phosphatase; SARS-CoV; Sirtuin; Reverse Transcriptase; Topoisomerase; Parasite	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
	Suramin Sodium Salt (BAY-205) 是可逆的竞争性蛋白酪氨酸磷酸酶抑制剂。它抑制 IP5K，是抗寄生虫，抗肿瘤和抗血管生成剂。它是sirtuins 的有效抑制剂，也是 SARS-CoV-2 RNA 依赖性 RNA 聚合酶抑制剂。
T16708	R-268712	ALK; TGF-beta/Smad	Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
	R-268712 是选择性的 ALK5 抑制剂(IC50:2.5 nM)。
T13613	ChX710	STING	Immunology/Inflammation
	ChX710可以引发 I 型干扰素对细胞溶质 DNA 的反应，其特异性细胞干扰素刺激基因 (ISG) 诱导 ISRE 启动子序列和干扰素调节因子 (IRF) 3 的磷酸化。
T62483	CJJ300	TGF-beta/Smad	Stem Cells
	CJJ300 是一种转化生长因子-β（TGF-β）抑制剂（IC50 : 5.3 μM）。CJJ300 通过破坏 TGF-β-TβR-I-TβR-II 信号传导复合物的形成来抑制 TGF-β 信号传导。CJJ300 可抑制细胞迁移。
T12006	Metarrestin ML246	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Metarrestin (ML246) 是一种口服有效的选择性核仁周区室 (PNC) 抑制剂，可有效抑制转移。Metarrestin 破坏核仁结构并抑制 RNA 聚合酶 (Pol) I 转录，部分是通过与翻译延伸因子 eEF1A2 的相互作用。
T2368L	Edoxaban Lixiana,依杜沙班	Factor Xa; Thrombin	Metabolism; Proteases/Proteasome
	Edoxaban (Lixiana) (DU-176) 是一种选择性的，口服有效的 factor Xa (FXa)抑制剂。Edoxaban 对游离 FXa 和凝血酶原的 Ki 分别为 0.561 nM 和 2.98 nM。Edoxaban 是一种抗凝剂，可用于预防中风。Edoxaban 还是一种凝血酶和凝血因子 IXaβ (FIXa) 的弱抑制剂，Ki 值分别为 6.00 μM 和 41.7 μM，对 FXa 的选择性超过 10000 倍。由于具有抗血栓形成的特性，Edoxaban 可用于预防血栓栓塞性疾病的研究。
T9088	Topovale ARC111,ARC 111,ARC-111,Topoval	Topoisomerase	DNA Damage/DNA Repair
	Topovale (ARC111) 是一种有效的拓扑异构酶 I 抑制剂。Topovale 抑制缺氧介导的缺氧诱导因子 1alpha 的积累。 Topovale 对一组癌细胞表现出低 nM 细胞毒性。与 P388 细胞相比，在 CPT 抗性拓扑异构酶 I (TOP1) 缺陷的 P388/CPT45 细胞中，Topovale 细胞毒性和 Topovale 诱导的细胞凋亡减少了 > 100 倍。
T4027	KIN1148	Influenza Virus	Microbiology/Virology
	KIN1148 是一种新型小分子佐剂，是IRF3激动剂，用于增强流感疫苗效率。
T70568	H-1356
	H-1356 is an insulin-like growth factor 1(IGF-I) analog that inhibits autophosphorylation of IGF-I receptor.
T68333	Galunisertib Monohydrate
	Galunisertib Monohydrate is a first-in-class transforming growth factor-β receptor type I inhibitor.
T69212	LY-580276
	LY-580276 is an inhibitor of the type I transforming growth factor beta receptor (TβRI).
T27224	DX-9065A HCl hydrate DX9065,DX 9065,DX9065A,DX 9065A,DX-9065A,DX-9065
	DX-9065A is a factor Xa inhibitor. DX-9065a inhibits proinflammatory events induced by factor Xa and gingipains. DX-9065a is a competitive inhibitor of the Spectrozyme FXa (SpFXa) cleavage by both fXa and prothrombinase with similar K(i) values of approxi
T79124	JGK-068S	EGFR	Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	JGK-068S（化合物I）是EGFR抑制剂，具有高效作用。
T29493	A 17002 C A-17002 C,A17002 C,A17002C,A 17002C,A-17002C
	A 17002 C is a form of madumycin I. It is a metabolite produced by Actinoplanes strains, structurally related to the virginiamycin factor M.
T27698	JTV-803 mesylate JTV803,JTV 803,JTV-803
	JTV-803 is a factor Xa inhibitor. JTV-803 showed a competitive inhibitory effect on human factor Xa, with a K(i) value of 0.019 microM and IC(50) value of 0.081 microM. JTV-803 was 100 times more selective in inhibiting human factor Xa as compared to its
T62597	TEAD-IN-3
	TEAD-IN-3 (compound I-177) 是一种 TEAD 转录因子的有效抑制剂。TEAD-IN-3 能够用于增生性疾病的研究，如癌症。
T76014	IGF-I (24-41) (TFA)
	IGF-I (24-41) TFA（Insulin-like Growth Factor I (24-41) TFA）是类胰岛素生长因子I的一个氨基酸片段，覆盖24至41位点。作为一种70个氨基酸组成的多肽激素，IGF-I TFA对神经元和神经胶质细胞具有营养作用，而且在调节全身生长激素（GH）活性中扮演关键角色。它还具备合成代谢、抗氧化、抗炎及细胞保护功能，对躯体生长及行为发育调节作用显著。
T73702	Mecasermin
	Mecasermin（Human IGF-I; FK 780），一种重组人胰岛素样生长因子I（IGF-I），主要用于研究因生长激素（GH）受体缺陷或GH抑制抗体导致的GH不敏感性而引起的生长障碍。
T82361	FXIIa-IN-1
	XIIa-IN-1-IN-3（Compound 22）作为一种Factor XIIa抑制剂，其Kiapp值为97.8 nM。该化合物主要应用于血栓形成的研究。
T39223	Milvexian JNJ-70033093,BMS-986177
	Milvexian (BMS-986177) is a potent antithrombotic compound that inhibits human and rabbit factor XIa (FXIa) directly and reversibly. It is orally-bioavailable and exhibits a K i of 0.11 nM and 0.38 nM against human and rabbit FXIa, respectively.
TP1361	S961 TFA (1083433-49-1 free base) S961 TFA
	S961 TFA is A high affinity insulin receptor (IR) antagonist with IC50 for hir-a, hir-b and human insulin-like growth factor I receptor (higf-ir) at 0.048, 0.027 and 630 nM, respectively.
T61506	NBI-31772 hydrate
	NBI-31772 hydrate is a powerful inhibitor of the interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). It acts as a nonpeptide ligand, effectively releasing bioactive IGF-I from the IGF-I/IGFBP-3 complex (Ki values for all six human subtypes range from 1-24 nM). This compound demonstrates significant anxiolytic and antidepressant-like effects [1] [2] [3].
T82360	FXIIa-IN-2
	XIIa-IN-1-IN-2（Compound 21）为一种高效的Factor XIIa抑制剂，具有Kiapp为62.2 nM。该化合物适用于血栓形成的研究领域。
T76012	IGF-I (30-41) (TFA)
	IGF-I (30-41) (TFA) 是类胰岛素生长因子I 30 至 41 的氨基酸片段。IGF-I 对生长激素的活性有着重要的作用，但是IGF-I 本身也具有一些自身的特性，如合成代谢、抗氧化、抗炎和细胞保护作用。
T39029	APC-6860
	APC-6860 is a trypsin-like serine proteases inhibitor with k i values of 0.21, 0.44, 1.5, 16.8, 20, 30 μM for uPA, trypsin, tryptase, tPA, thrombin and factor Xa, respectively. APC-6860 has a selectivity ratio for tPA versus uPA of 80. APC-6860 has k i values of 0.1, 0.082 μM for human and murine urokinases, respectively. APC-6860 can be used for the research of cancer.
TP1795	S961
	S961是一种高亲和力和选择性胰岛素受体(IR)拮抗剂，接近闪烁计数法试验中对HIR-A、HIR-B 和人胰岛素样生长因子I 受体(HIGF-IR)的ic50分别为0.048、0.027和630 nM。
T76043L	S961 acetate
	S961 acetate 是一种高亲和力的胰岛素受体 (insulin receptor, IR) 拮抗剂，对 HIR-A，HIR-B 和人胰岛素样生长因子 I 受体 (HIGF-IR) 的 IC50分别为 0.048，0.027 和 630 nM。
T76043	S961 TFA
	S961 TFA为一种与胰岛素受体（insulin receptor, IR）高亲和力相结合的拮抗剂，其IC50值对HIR-A、HIR-B及人胰岛素样生长因子I受体（HIGF-IR）分别为0.048、0.027及630 nM。
T77221	Benzenecarboximidamide, hydrochloride, hydrate (1:1:x)
	Benzenecarboximidamide, hydrochloride, hydrate (1:1:x) (Benzamidine hydrochloride hydrate) 是一种可逆的竞争性胰蛋白酶样丝氨酸蛋白酶 (trypsin-like serine proteases) 抑制剂，对 Tryptase、Trypsin、uPA、Factor Xa、Thrombin 和 tPA 的Ki 值分别为 20、21、97、110、320 和 750 μM。
T69205	GGTI-2166
	GGTI-2166 is a geranylgeranyl transferase I inhibitor. GGTI-2166 inhibit the pOC formation induced by RANKL or TNF-alpha in cultures of both mouse marrow-derived macrophage-colony-stimulating factor (M-CSF) dependent monocytes (MD cells) and the mouse monocyte cell line RAW 264.7 (RAW cells). GGTI-2166 inhibited TRAP activity induced by RANKL or TNF-alpha in both cell cultures and prevented the incorporation of [3H]all-trans geranylgeraniol into prenylated proteins in RAW cells.
T63070	EGFR-IN-45
	EGFR-IN-45 是一种有效的表皮生长因子受体 (EGFR) 泛抑制剂，能够作用于 EGFR (IC50: 0.4 μM) 和 CDK2 (IC50: 1.6 μM)。EGFR-IN-45 对拓扑异构酶 Topo I 和 Topo II 也具有抑制作用。EGFR-IN-45 能将癌细胞的细胞周期阻滞在 G1 前期，并诱导细胞凋亡 (apoptosis)。
T38329	CU-76
	CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS; IC50= 0.24 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. CU-76 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM. 1.Padilla-Salinas, R., Sun, L., Anderson, R., et al.Discovery of small-molecule cyclic GMP-AMP sy...
T38328	CU-32
	CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. It is also selective for cGAS over toll-like receptors (TLRs) at 50 μM. CU-32 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM. 1.Padilla-Salinas...
T36373	Urocortin II (mouse) (trifluoroacetate salt)
	Urocortin II is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin III , frog sauvagine, and piscine urotensin I.1 Mouse urocortin II shares 34 and 42% sequence homology with rat CRF and urocortin . It is expressed in mouse paraventricular, supraoptic, and arcuate nuclei of the hypothalamus, the locus coeruleus, and in motor nuclei of the brainstem and spinal ventral horn. Urocortin II selectively binds to CRF...
T77038	Interferon alfa
	Interferon alfa 是 I 型干扰素，可激活新基因，对靶细胞产生有效抗病毒和抗增殖活性。Interferon alfa 的信号传导需要 Stat1和 Stat2 的受体依赖性激活，形成异源二聚化 STAT。STAT 复合物与 DNA 结合蛋白 IRF-9 (p48) 结合并形成 ISGF-3 (IFN 刺激基因因子 3)。随后由 ISGF-3 进一步激活驱动基因，实现抗病毒功能。
T38228	R 121919 hydrochloride
	High affinity corticotropin releasing factor receptor1 (CRF1) antagonist (Ki = 3.5 nM). Reduces stress-induced elevations of plasma ACTH. Anxiolytic and antidepressant in vivo. Orally bioavailable. Chen and Grigoriadis (2005) NBI 30775 (R121919), an orally active antagonist of the corticotropin-releasing factor (CRF) type-1 receptor for the treatment of anxiety and depression. Drug Dev.Res. 65 216 \|Jutkiewicz et al (2005) The effects of CRF antagonists, antalarmin, CP154,526, LWH234, and R121919...

化合物

IGF-I 30-41 acetate(82177-09-1 free base)

Cat.No: TP1122L

Synonym: Insulin-like Growth Factor I (30-41) acetate

Target: Others

Cat.No: T4026

Synonym: VEGFR2 Kinase Inhibitor I

Target: VEGFR

Complement factor I

Cat.No: T80059

Target: Endogenous Metabolite

Multi-kinase inhibitor 1

Cat.No: T4191

Synonym: Multi-kinase inhibitor I

Target: Others, Bcr-Abl, PDGFR, c-Kit

Malachite green oxalate

Cat.No: TD0099

Target: Apoptosis, Others, IκB/IKK, NF-κB

Cat.No: T0708

Synonym: 奥沙普秦,Oxaprozinum,Wy21743

Target: NF-κB, COX

Cat.No: TP1122

Synonym: Insulin-like Growth Factor I (30-41),IGF-I 30-41

Cat.No: TP1124

Synonym: Insulin-like Growth Factor I (24-41),IGF-I 24-41

IGF-I (30-41) TFA(82177-09-1,FREE)

Cat.No: TP1121

Synonym: Insulin-like Growth Factor I (30-41) (TFA)

IGF-I (24-41) TFA (135861-49-3 free base)

Cat.No: TP1123

Synonym: Insulin-like Growth Factor I (24-41) (TFA),IGF-I (24-41) TFA

Cat.No: T25465

Synonym: GS-143,GS 143

Target: IκB/IKK, E1/E2/E3 Enzyme, NF-κB

Cat.No: T1944

Target: ALK, TGF-beta/Smad

Theophylline monohydrate

Cat.No: T1083L

Synonym: Quibron,茶碱一水合物

Target: HDAC, PDE, Adenosine Receptor

Urocortin, human

Cat.No: TP1021

Synonym: Urocortin (human),Human urocortin,Human urocortin 1,Human urocortin I

Target: CRFR

Suramin Sodium Salt

Cat.No: T2160

Synonym: 苏拉明钠,BAY-205,Suramin hexasodium salt,苏拉明钠盐,NF-060

Target: Apoptosis, Phosphatase, SARS-CoV, Sirtuin, Reverse Transcriptase, Topoisomerase, Parasite

Cat.No: T16708

Target: ALK, TGF-beta/Smad

Cat.No: T13613

Target: STING

Cat.No: T62483

Target: TGF-beta/Smad

Cat.No: T12006

Synonym: ML246

Target: DNA/RNA Synthesis

Cat.No: T2368L

Synonym: Lixiana,依杜沙班

Target: Factor Xa, Thrombin

Cat.No: T9088

Synonym: ARC111,ARC 111,ARC-111,Topoval

Target: Topoisomerase

Cat.No: T4027

Target: Influenza Virus

Cat.No: T70568

Galunisertib Monohydrate

Cat.No: T68333

Cat.No: T69212

DX-9065A HCl hydrate

Cat.No: T27224

Synonym: DX9065,DX 9065,DX9065A,DX 9065A,DX-9065A,DX-9065

Cat.No: T79124

Target: EGFR

Cat.No: T29493

Synonym: A-17002 C,A17002 C,A17002C,A 17002C,A-17002C

JTV-803 mesylate

Cat.No: T27698

Synonym: JTV803,JTV 803,JTV-803

Cat.No: T62597

IGF-I (24-41) (TFA)

Cat.No: T76014

Cat.No: T73702

Cat.No: T82361

Cat.No: T39223

Synonym: JNJ-70033093,BMS-986177

S961 TFA (1083433-49-1 free base)

Cat.No: TP1361

Synonym: S961 TFA

NBI-31772 hydrate

Cat.No: T61506

Cat.No: T82360

IGF-I (30-41) (TFA)

Cat.No: T76012

Cat.No: T39029

Cat.No: TP1795

Cat.No: T76043L

Cat.No: T76043

Benzenecarboximidamide, hydrochloride, hydrate (1:1:x)

Cat.No: T77221

Cat.No: T69205

Cat.No: T63070

Cat.No: T38329

Cat.No: T38328

Urocortin II (mouse) (trifluoroacetate salt)

Cat.No: T36373

Interferon alfa

Cat.No: T77038

R 121919 hydrochloride

Cat.No: T38228

Cat. No.	Product Name	Target	Signaling Pathways
T2801	Aristolochic acid A 马兜铃酸,TR 1736,Aristolochin,Aristolochine,Aristolochic Acid I,Aristolochic Acid	Others; NF-κB	NF-κB; Others
	Aristolochic acid A (TR 1736) 是植物提取物 Aristolochic acids 的主要成分，主要存在于 Aristolochia 和 Asarum 草本植物中。它降低人细胞中膀胱癌相关BLCAP 基因表达。它显著降低激活蛋白1 (AP-1) 和NF-κB 活性。
T5S0089	Kaempferol-3-O-glucorhamnoside Kaempferol 3-glucorhamnoside,百蕊草素I	Antioxidant; p38 MAPK; NF-κB	MAPK; NF-κB; oxidation-reduction
	Kaempferol-3-O-glucorhamnoside (Kaempferol 3-glucorhamnoside) 是来源于百蕊草的一种类黄酮，在体内外均能通过 MAPK 和 NF-κB 通路抑制炎症反应。
T2873	Ginsenoside Rg2 Chikusetsusaponin I,Panaxoside Rg2,人参皂苷Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2,人参皂苷 Rg2	Beta Amyloid; GSK-3; NF-κB	Neuroscience; NF-κB; PI3K/Akt/mTOR signaling; Stem Cells
	Ginsenoside Rg2 (Chikusetsusaponin I) 是一种人参的主要活性成分。它能够降低Aβ1-42积聚，抑制脂多糖介导的VCAM-1和ICAM-1表达的增加。
T6856	Halofuginone 卤夫酮,常山酮,Tempostatin,empostatin,RU-19110	Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Stem Cells
	Halofuginone (RU-19110) 是Febrifugine 的衍生物，是一种竞争性脯氨酰-tRNA 合成酶抑制剂。它也是肺血管扩张剂，可激活Kv 通道并阻断电压门控、受体操作和存储操作的钙离子通道。它具有抗炎、抗癌、抗疟疾和抗纤维化作用。
TWA2417	Sodium taurocholate 牛黄胆酸钠(牛胆酸钠，牛胆酸钠盐，牛磺膽酸鈉，牛磺胆酸钠，牛磺胆酸钠盐，牛胆酸钠水合物，水合牛磺胆酸钠，牛胆酸钠(混合物)，牛黄胆酸钠(水合)，牛磺胆酸钠(标准品)),Taurocholate Sodium	Others	Others
	Sodium taurocholate (Taurocholate Sodium) hydrate 具有显著的生物学效应，例如通过上调 VEGF-A 的表达抑制肝动脉结扎所致的胆道损伤。对免疫系统具有一定的调节作用。
T3524	Halofuginone hydrobromide 卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐	Others; Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Others; Stem Cells
	Halofuginone hydrobromid 是Febrifugine 的衍生物，是竞争性脯氨酰-tRNA 合成酶抑制剂。它是 I 型胶原合成的特异性抑制剂，并通过抑制TGF-β活性可减轻骨关节炎。它具有抗疟疾、抗炎、抗癌、抗纤维化作用。
T10233	Acetylarenobufagin	HIF	Angiogenesis; Chromatin/Epigenetic
	Acetylarenobufagin 是一种类固醇缺氧诱导因子-1 (HIF-I) 调节剂。
T2787	Picroside I 6'-Cinnamoylcatalpol,胡黄连苦苷I	MMP; STAT	JAK/STAT signaling; Proteases/Proteasome; Stem Cells
	Picroside I (6'-Cinnamoylcatalpol) 是胡黄连的一种天然产物，是有肝脏保护作用的代谢成分，可用于哮喘研究，有减轻炎症作用，还下调 pSTAT6 和 GATA3 表达。
T2140	Parthenolide (-)-Parthenolide,小白菊内酯	Apoptosis; Mitophagy; NF-κB; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κB
	Parthenolide ((-)-Parthenolide) 是一种从药草短舌匹菊中发现的倍半萜内酯。它抑制NF-κB 活化，有抗炎活性。它还可抑制HDAC1蛋白，但不影响其他I/II 类HDAC。
TN2322	Yangambin	Calcium Channel; PAFR	GPCR/G Protein; Membrane transporter/Ion channel; Metabolism
	Yangambin 是从诸如番荔枝科植物中分离出来的呋喃木脂素，是选择性PAF 受体拮抗剂，通过调控Ca2+通道抑制 Ca2+流入，导致 [Ca2+]i 在血管平滑肌细胞和随后的外周血管舒张中减少，具有降压作用。
TN2217	Sophoflavescenol 槐苦参醇,槐黄醇	Others; Beta-Secretase; BACE; PDE; AChR; AChE	Metabolism; Neuroscience; Others
	Sophoflavescenol 是异戊烯基黄酮类化合物，能够抑制PDE5的活性，IC50=0.013 μM。它也抑制 RLAR，HRAR，BACE1，AChE 和 BChE，IC50值分别为 0.30 µM，0.17 µM，10.98 µM，8.37 µM 和 8.21 µM。

天然产物

Aristolochic acid A

Cat.No: T2801

Synonym: 马兜铃酸,TR 1736,Aristolochin,Aristolochine,Aristolochic Acid I,Aristolochic Acid

Target: Others, NF-κB

Kaempferol-3-O-glucorhamnoside

Cat.No: T5S0089

Synonym: Kaempferol 3-glucorhamnoside,百蕊草素I

Target: Antioxidant, p38 MAPK, NF-κB

Ginsenoside Rg2

Cat.No: T2873

Synonym: Chikusetsusaponin I,Panaxoside Rg2,人参皂苷Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2,人参皂苷 Rg2

Target: Beta Amyloid, GSK-3, NF-κB

Cat.No: T6856

Synonym: 卤夫酮,常山酮,Tempostatin,empostatin,RU-19110

Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Sodium taurocholate

Cat.No: TWA2417

Synonym: 牛黄胆酸钠(牛胆酸钠，牛胆酸钠盐，牛磺膽酸鈉，牛磺胆酸钠，牛磺胆酸钠盐，牛胆酸钠水合物，水合牛磺胆酸钠，牛胆酸钠(混合物)，牛黄胆酸钠(水合)，牛磺胆酸钠(标准品)),Taurocholate Sodium

Target: Others

Halofuginone hydrobromide

Cat.No: T3524

Synonym: 卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐

Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Acetylarenobufagin

Cat.No: T10233

Target: HIF

Cat.No: T2787

Synonym: 6'-Cinnamoylcatalpol,胡黄连苦苷I

Target: MMP, STAT

Cat.No: T2140

Synonym: (-)-Parthenolide,小白菊内酯

Target: Apoptosis, Mitophagy, NF-κB, HDAC, Autophagy

Cat.No: TN2322

Target: Calcium Channel, PAFR

Sophoflavescenol

Cat.No: TN2217

Synonym: 槐苦参醇,槐黄醇

Target: Others, Beta-Secretase, BACE, PDE, AChR, AChE

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPK-01023	Complement factor I Protein, Mouse, Recombinant (His) FIC3b-INA,I factor (comp...	Mouse	HEK293 Cells
	Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 66.39 kDa and the accession number is Q61129.
TMPK-00776	Complement factor I Protein, Human, Recombinant (His) FIC3b-INA,KAF,IF,CFI,	Human	HEK293 Cells
	Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64.58 kDa and the accession number is P05156.
TMPH-03273	Complement factor I Protein, Rat, Recombinant (His & Myc) If,Complement factor I,Cfi	Rat	Baculovirus Insect Cells
	Complement factor I Protein, Rat, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 69.2 kDa and the accession number is Q9WUW3.
TMPY-06982	IGF1/IGF-I Protein, Human, Recombinant insulin-like growth factor	Human	E. coli
	IGF1/IGF-I Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 KDa. and the accession number is P05019-1.
TMPY-04878	IGF1/IGF-I Protein, Mouse, Recombinant insulin-like growth factor	Mouse	P. pastoris (Yeast)
	IGF1/IGF-I Protein, Mouse, Recombinant is expressed in yeast. The predicted molecular weight is 7.7 kDa and the accession number is E9PU89.
TMPY-00834	IGF1R/CD221 Protein, Human, Recombinant (His) IGF-I R,IGFR,IGFI	Human	HEK293 Cells
	IGF1R/CD221 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81 kDa and the accession number is P08069.
TMPY-02535	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) TNFalpha-R1,TNFAR,TNF-R-I,TNF-R,TNFRp55,FPF,TNF-R55...	Mouse	HEK293 Cells
	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.4 kDa and the accession number is P25118.
TMPY-01459	TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) p60,TNFR60,TNFAR,TBP1,CD120a,TNFR1-d2,TNFR1,TNF-R-I...	Human	HEK293 Cells
	TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1.
TMPH-01306	EIF4A1 Protein, Human, Recombinant (His & Myc) eIF4A-I,EIF4A1,eIF-4A-	Human	E. coli
	ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon. EIF4A1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The ...
TMPJ-00280	TNF R1 Protein, Mouse, Recombinant Tnfrsf1a,Tumor necrosis factor receptor su...	Mouse	E. coli
	Tumor necrosis factor receptor superfamily member 1A (Tnfrsf1a) is a member of the tumor necrosis factor receptor superfamily. Tnfrsf1a is one of the major receptors for the tumor necrosis factor-alpha. It can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the...
TMPY-04942	IGF1 LR3 Protein, Human, Recombinant IGF‑I,insulin-li	Human	P. pastoris (Yeast)
	IGF1 LR3 Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 9.1 kDa and the accession number is P05019-1.
TMPJ-00781	LR3-IGF-1 Protein, Mouse, Recombinant (His) IGF1,insulin-like growth...	Mouse	E. coli
	Insulin-like growth factor I (IGF1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mouse IGF-I is synthesized as two precursor isoforms with alternate N- and C-terminal propeptides. These isoforms are differentially expressed by various tissues. Mature mouse IGF-I shares 94% and 99% aa sequence identity with human and rat IGF-I, respectively, and exhibits cross-species activity. It shares 60% aa sequence identity with mature mouse IGF-II. IG...
TMPJ-00020	IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated 白介素,Eosinophil differenti	Human	HEK293 Cells
	IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cells and eosinophils. Relative to B cells, IL-5 appears to induce the differentiation of activated conventional B-2 cells into Ig-secreting cells. In addition, it induces the growth of B-1 progenitors as well as IgM production by B-1 cells.IL-5 appears to perform a number of functi...
TMPY-01769	4EBP1 Protein, Human, Recombinant (His) 4E-BP1,eukaryotic translation in<...	Human	E. coli
	The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcription factor activating transcription factor-4 (ATF4), a master regulator of gene expression in stress responses. 4E-BP1 is characterized by its capacity to bind specifically to eIF4E and inhibit its interaction with eIF4G. Phosphorylation of 4E-BP1 regulates eIF4E availability, a...
TMPY-06905	IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated CD221,insulin-like growth fac...	Human	HEK293 Cells
	IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 106.14 kDa and the accession number is NP_000866.1.
TMPY-04360	IGF1R/CD221 Protein, Human, Recombinant (His & GST) JTK13,insulin-like growth fac...	Human	Baculovirus Insect Cells
	IGF1R/CD221 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 74.6 kDa and the accession number is P08069.
TMPH-03289	EIF3I Protein, Rat, Recombinant (E. coli, His) eIF3 p36,eIF3i,eIF-3-bet...	Rat	E. coli
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly an...
TMPH-03288	EIF3I Protein, Rat, Recombinant (His) eIF3i,Eif3s2,eIF-3-beta,...	Rat	Baculovirus Insect Cells
	Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly an...
TMPY-04366	ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) LDS1,ALK-5,LDS2A,AAT5,SKR4,transforming growth ...	Human	Baculovirus Insect Cells
	ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 62.6 kDa and the accession number is P36897-1.
TMPY-05771	ALK-5 Protein, Human, Recombinant (hFc) AAT5,SKR4,TGFR-1,LDS1,transforming growth facto...	Human	HEK293 Cells
	ALK-5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36.87 kDa and the accession number is P36897-1.
TMPY-01358	ALK-5 Protein, Human, Recombinant (His & hFc) tβR-I,ALK5,AAT5,TGFR-1,LDS2A,LDS1,transformi	Human	HEK293 Cells
	ALK-5 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 38.1 kDa and the accession number is P36897-1.
TMPY-01639	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His) TNFalpha-R1,TNFRp55,CD120a,TNF-alphaR1,FPF,p55-R,TNF-R,TNFAR...	Mouse	HEK293 Cells
	TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.8 kDa and the accession number is P25118.
TMPY-05475	TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc) MS5,p55-R,p60,TNFR1-d2,TNFR55,TNFR1,tumor necrosis ...	Human	HEK293 Cells
	TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P19438-1.
TMPJ-00261	TGF beta 2 Protein, Mouse/Rat, Recombinant transforming growth factor β-2,BSC-1 cell ...	Mouse,Rat	HEK293 Cells
	Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the n...
TMPY-01009	TGFBI Protein, Human, Recombinant (His) CDG2,CSD,EBMD,CSD1,CDGG1,CSD3,transforming growth <...	Human	HEK293 Cells
	TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondral bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dys...
TMPY-02185	Coagulation factor XIII B/F13B Protein, Human, Recombinant (His) Coagulation factor 13,coagulation...	Human	HEK293 Cells
	Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ( CCP / SCR ) domains. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have en...
TMPJ-00994	LTBR Protein, Mouse, Recombinant (hFc) Tnfcr,Lymphotoxin-beta receptor,Tumor necrosi	Mouse	HEK293 Cells
	It is a single-pass type I membrane protein and contains 4 TNFR-Cys repeats. The protein is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein is the receptor for the heterotrimeric lymphotoxin containing LTA and LTB, and for TNFS14/LIGHT. It promotes apoptosis via TRAF3 and TRAF5 and may play a role in the development of lymphoid organs...
TMPK-00083	IGF1/IGF-I Protein, Human, Recombinant (hFc) IGF1A,胰岛素样生长因子,IBP1,IGF-I	Human	HEK293 Cells
	The insulin family consists of insulin, insulin-like growth factor 1 (IGF-1), insulin-like growth factor 2 (IGF-2), their receptors (IR, IGF-1R and IGF-2R), and their binding proteins.Insulin-like growth factor I (IGF-I) is a polypeptide hormone produced mainly by the liver in response to the endocrine GH stimulus, but it is also secreted by multiple tissues for autocrine/paracrine purposes.
TMPH-01799	Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)	Human	E. coli
	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 95.2 kDa and the accession number is P17480.
TMPH-01798	Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)	Human	E. coli
	Recognizes the ribosomal RNA gene promoter and activates transcription mediated by RNA polymerase I through cooperative interactions with the transcription factor SL1/TIF-IB complex. It binds specifically to the upstream control element. Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO tag. The predicted molecular weight is 107.9 kDa and the accession number is P17480.
TMPH-01702	SMAD6 Protein, Human, Recombinant (E. coli, His & Myc)	Human	E. coli
	Transforming growth factor-beta superfamily receptors signaling occurs through the Smad family of intracellular mediators. SMAD6 is an inhibitory Smad (i-Smad) that negatively regulates signaling downstream of type I transforming growth factor-beta. Acts as a mediator of TGF-beta and BMP anti-inflammatory activities. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory gen...
TMPJ-00123	FLT3LG Protein, Mouse, Recombinant (His) Fms-related tyrosine kinase 3 lig...	Mouse	HEK293 Cells
	Fms-related tyrosine kinase 3 ligand(Flt3L) is a single-pass type I membrane protein and consists of 232 amino acids. Flt3L is a hematopoietic four helical bundle cytokine, structurally homologous to stem cell factor and colony stimulating factor. Flt3L synergizes well with a number of other colony stimulating factors and interleukins. Flt3L stimulates the proliferation and differentiation of various blood cell progentiors by activating FLT3.
TMPK-00428	HER2/ErbB2 Protein, Human, Recombinant (His & Avi) MLN 19,HER2,HER-2,HERVW,EGFR2,ENV,ERBB2,NEU,HERV7Q,ERVWE1,EN...	Human	HEK293 Cells
	ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors.Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane.
TMPK-00570	CD46 Protein, Canine, Recombinant (His) CD46,AHUS2,TRA2.10,LOC609365,TLX,MCP,MIC10,Membrane...	Canine	HEK293 Cells
	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'. CD46 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells w...
TMPK-00532	CD46 Protein, Cynomolgus, Recombinant (His) CD46,MCP,TLX,MIC10,AHUS2,TRA2.10	Cynomolgus	HEK293 Cells
	CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated 'self-attack'. CD46 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cel...
TMPH-02606	CR1L Protein, Mouse, Recombinant (His) Crry,Complement regulatory protein Crry,Complement ...	Mouse	E. coli
	Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion. CR1L Prot...
TMPK-01027	IGFBP-7 Protein, Mouse, Recombinant (hFc) TAF,RAMSVPS,IBP7,PSF,IGFBP-7,MAC25,I	Mouse	HEK293 Cells
	IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Mouse, Recombinant (hFc) is expres...
TMPJ-00274	LTBR Protein, Human, Recombinant (His) TNFCR,Tumor Necrosis Factor Receptor Super...	Human	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 3, also known as Lymphotoxin-beta receptor,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis factor receptor type III,LTBR,TNFCR, TNFR3 and TNFRSF3, is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types, but not on T and B lymphocytes. LTBR and its ligand p...
TMPJ-00572	Vasorin Protein, Human, Recombinant (His) Vasorin,VASN,SLITL2,Protein Sl	Human	HEK293 Cells
	Vasorin is a Type I membrane protein, which is predominantly expressed in vascular smooth muscle cells in a developmentally regulated pattern. The expression level of Vasorin can be down regulated during vessel repair after arterial injury. Vasorin binds to transforming growth factor beta (TGF-β) and attenuates TGF-β signaling in vitro.
TMPK-01371	IGFBP-7 Protein, Human, Recombinant (hFc) RAMSVPS,TAF,IGFBPRP1,AGM,IBP7,MAC25,I<...	Human	HEK293 Cells
	IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion. IGFBP-7 Protein, Human, Recombinant (hFc) is expres...
TMPU-00003	STAT2 Protein, Human, Recombinant (His)	Human	E. coli
	Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of...
TMPY-03329	DPEP1 Protein, Human, Recombinant (His) MBD1,dipeptidase 1,MDP,RDP	Human	HEK293 Cells
	Dehydropeptidase-I, also known as DPEP1, is a kidney membrane enzyme. Its expression in normal colonic mucosa is very low, but it is highly expressed in colorectal adenoma and cancer specimens and is negatively correlated with parameters of pathological aggressiveness and poor prognosis. The overexpression of DPEP1 suppressed tumor cells invasiveness and increased sensitivity to chemotherapeutic agent Gemcitabine. Growth factor EGF treatment decreased DPEP1 expression. Dehydropeptidase-I m...
TMPJ-00973	EIF1AX Protein, Human, Recombinant (His) eIF-1A X Isoform,Eukaryotic Trans...	Human	E. coli
	Eukaryotic Translation Initiation Factor 1A, X-Chromosomal (EIF1AX) is an essential eukaryotic translation initiation factor that belongs to the eIF-1A family. EIF1AX is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA and has been shown to interact with IPO13. EIF1AX contains one S1-like domain and seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the bind...
TMPJ-00314	ACVR2B Protein, Human, Recombinant (hFc & His) ACVR2B,Activin Receptor Type I	Human	HEK293 Cells
	Activin proteins that belong to the transforming growth factor-beta (TGF-β) superfamily, exert their biological actions by binding to heteromeric receptor complexes of type I and type II serine/threonine kinase receptors. On ligand binding, type I and II receptors form a stable complex, resulting in phosphorylation of type I receptors by type II receptors with constitutive kinase activity, and subsequently initiates the activation of downstream molecules including the endogenous Smads. ActRIIB, ...
TMPJ-00315	ACVR2A Protein, Human, Recombinant (hFc & His) ACTR-IIA,Activin Recepto...	Human	HEK293 Cells
	Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors....
TMPY-01710	IkB alpha/NFKBIA Protein, Human, Recombinant (His) IkB α,IKBA,nuclear factor of kapp...	Human	E. coli
	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IkB alpha, NFKBIA, or IKBA), is a member of the NF-kappa-B inhibitor family that function to inhibit the NF-kB transcription factor. NFKBIA inhibits NF-kB by masking the nuclear localization signals (NLS) of NF-kB proteins and keeping them sequestered in an inactive state in the cytoplasm. Also, NFKBIA blocks the ability of NF-κB transcription factors to bind to DNA, which is required for NF-kB's proper function...
TMPJ-00809	CFH Protein, Human, Recombinant (His) CFH,Complement factor H	Human	HEK293 Cells
	Complement Factor H (CFH) is a secreted protein which is a member of the regulators of complement activation family and is a complement control protein. It is expressed by the liver and secreted in plasma. Its principal function is to regulate the Alternative Pathway of the complement system, ensuring that the complement system is directed towards pathogens or other dangerous material and does not damage host tissue. Factor H regulates complement activation on self cells and surfaces by possessi...
TMPJ-00535	F13A Protein, Human, Recombinant (His) F13A1,Coagulation Factor XII<...	Human	HEK293 Cells
	Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have enzymatic activity and may serve as plasma carrier molecules. Platelet factor XIII is composed of just 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium io...
TMPJ-00358	DR6 Protein, Mouse, Recombinant (hFc & His) BM-018,CD358,DR6,Tnfrsf21,Tumor necrosis factor...	Mouse	HEK293 Cells
	Tumor necrosis factor receptor superfamily member 21(DR6) is a single-pass type I membrane protein and contains 1 death domain and 4 TNFR-Cys repeats. The protein may activate NF-kappa-B and promote apoptosis and it may activate JNK and be involved in T-cell differentiation.It is required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragm...
TMPH-03038	Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO) Cobra venom factor,Complement C3 homolog,CVFk,CVF	Naja kaouthia	E. coli
	Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely re...
------------------------ 更多 ------------------------

重组蛋白

Complement factor I Protein, Mouse, Recombinant (His)

Cat.No: TMPK-01023

Species: Mouse

Expression System: HEK293 Cells

Complement factor I Protein, Human, Recombinant (His)

Cat.No: TMPK-00776

Species: Human

Expression System: HEK293 Cells

Complement factor I Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03273

Species: Rat

Expression System: Baculovirus Insect Cells

IGF1/IGF-I Protein, Human, Recombinant

Cat.No: TMPY-06982

Species: Human

Expression System: E. coli

IGF1/IGF-I Protein, Mouse, Recombinant

Cat.No: TMPY-04878

Species: Mouse

Expression System: P. pastoris (Yeast)

IGF1R/CD221 Protein, Human, Recombinant (His)

Cat.No: TMPY-00834

Species: Human

Expression System: HEK293 Cells

TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02535

Species: Mouse

Expression System: HEK293 Cells

TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)

Cat.No: TMPY-01459

Species: Human

Expression System: HEK293 Cells

EIF4A1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01306

Species: Human

Expression System: E. coli

TNF R1 Protein, Mouse, Recombinant

Cat.No: TMPJ-00280

Species: Mouse

Expression System: E. coli

IGF1 LR3 Protein, Human, Recombinant

Cat.No: TMPY-04942

Species: Human

Expression System: P. pastoris (Yeast)

LR3-IGF-1 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00781

Species: Mouse

Expression System: E. coli

IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPJ-00020

Species: Human

Expression System: HEK293 Cells

4EBP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01769

Species: Human

Expression System: E. coli

IGF1R/CD221 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06905

Species: Human

Expression System: HEK293 Cells

IGF1R/CD221 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04360

Species: Human

Expression System: Baculovirus Insect Cells

EIF3I Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPH-03289

Species: Rat

Expression System: E. coli

EIF3I Protein, Rat, Recombinant (His)

Cat.No: TMPH-03288

Species: Rat

Expression System: Baculovirus Insect Cells

ALK-5 Protein, Human, Recombinant (aa 200-503, His & GST)

Cat.No: TMPY-04366

Species: Human

Expression System: Baculovirus Insect Cells

ALK-5 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05771

Species: Human

Expression System: HEK293 Cells

ALK-5 Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-01358

Species: Human

Expression System: HEK293 Cells

TNFR1/CD120a/TNFRSF1A Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01639

Species: Mouse

Expression System: HEK293 Cells

TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-05475

Species: Human

Expression System: HEK293 Cells

TGF beta 2 Protein, Mouse/Rat, Recombinant

Cat.No: TMPJ-00261

Species: Mouse,Rat

Expression System: HEK293 Cells

TGFBI Protein, Human, Recombinant (His)

Cat.No: TMPY-01009

Species: Human

Expression System: HEK293 Cells

Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)

Cat.No: TMPY-02185

Species: Human

Expression System: HEK293 Cells

LTBR Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00994

Species: Mouse

Expression System: HEK293 Cells

IGF1/IGF-I Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00083

Species: Human

Expression System: HEK293 Cells

Nucleolar transcription factor 1 Protein, Human, Recombinant (E. coli, His & SUMO)

Cat.No: TMPH-01799

Species: Human

Expression System: E. coli

Nucleolar transcription factor 1 Protein, Human, Recombinant (Cell-Free, His & SUMO)

Cat.No: TMPH-01798

Species: Human

Expression System: E. coli

SMAD6 Protein, Human, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-01702

Species: Human

Expression System: E. coli

FLT3LG Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00123

Species: Mouse

Expression System: HEK293 Cells

HER2/ErbB2 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00428

Species: Human

Expression System: HEK293 Cells

CD46 Protein, Canine, Recombinant (His)

Cat.No: TMPK-00570

Species: Canine

Expression System: HEK293 Cells

CD46 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00532

Species: Cynomolgus

Expression System: HEK293 Cells

CR1L Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02606

Species: Mouse

Expression System: E. coli

IGFBP-7 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-01027

Species: Mouse

Expression System: HEK293 Cells

LTBR Protein, Human, Recombinant (His)

Cat.No: TMPJ-00274

Species: Human

Expression System: HEK293 Cells

Vasorin Protein, Human, Recombinant (His)

Cat.No: TMPJ-00572

Species: Human

Expression System: HEK293 Cells

IGFBP-7 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-01371

Species: Human

Expression System: HEK293 Cells

STAT2 Protein, Human, Recombinant (His)

Cat.No: TMPU-00003

Species: Human

Expression System: E. coli

DPEP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-03329

Species: Human

Expression System: HEK293 Cells

EIF1AX Protein, Human, Recombinant (His)

Cat.No: TMPJ-00973

Species: Human

Expression System: E. coli

ACVR2B Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00314

Species: Human

Expression System: HEK293 Cells

ACVR2A Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00315

Species: Human

Expression System: HEK293 Cells

IkB alpha/NFKBIA Protein, Human, Recombinant (His)

Cat.No: TMPY-01710

Species: Human

Expression System: E. coli

CFH Protein, Human, Recombinant (His)

Cat.No: TMPJ-00809

Species: Human

Expression System: HEK293 Cells

F13A Protein, Human, Recombinant (His)

Cat.No: TMPJ-00535

Species: Human

Expression System: HEK293 Cells

DR6 Protein, Mouse, Recombinant (hFc & His)

Cat.No: TMPJ-00358

Species: Mouse

Expression System: HEK293 Cells

Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)

Cat.No: TMPH-03038

Species: Naja kaouthia

Expression System: E. coli

--------- 更多 ---------

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼